"Dreamer" or dreMR is an extension to MRI which allows us to quantitatively measure biological processes within the body, noninvasively. 

The underlying principle of dreMR is that we can inject "dispersive" contrast agents into the subject, which bind with target molecules. The dispersive property of these agents means that they produce a signal under MRI with amplitude (relaxivity) highly dependent on magnetic field strength in addition to their local concentration. 

With dreMR, we can shift the MRI main magnetic field strength by use of an insertable electromagnetic coil, to measure this signal at different field strengths and produce fused signal proportional to local concentration of some molecule.

Assumptions in the development of dreMR included instantaneous ramping of the insert coil and perfectly homogeneous field shifts. Here we discard these assumptions and show that finite ramping and field inhomogeneities impair proportionality to agent concentration and produce significant signal from background tissues.

Previous dreMR hardware consisted of a shielded, thick solenoid with a central axial split. Our new design method uses a uniform thick solenoid with an inner layer of windings specifically placed to improve field homogeneity. The design of this inner layer is coupled with that of the shield, allowing for simultaneous improvement of both homogeneity and shielding.